Additionally, the database is limited to deals valued at a minimum of $50 million upfront. ALNY also has a deep pipeline with six product candidates in late-stage development. Hunzinger said: Biotech and smaller medical device deals should continue in the first half of the year, with the second half poised for larger deals driven by a need for scale and an expected settling of the regulatory landscape.. Leap Therapeutics, Inc. and Flame Biosciences, Inc. announced that the companies have entered into a definitive merger agreement pursuant to which Leap has acquired Flame and its assets, including FL-301, its clinical stage anti-Claudin18.2 monoclonal antibody, FL-302, its preclinical anti-Claudin18.2/CD137 bispecific monoclonal antibody, FL-501, its preclinical anti-GDF15 monoclonal antibody, and net cash of approximately $50 million as of December 31, 2022. For this story, BioPharma Dive looked only at companies developing human medicines. FierceBiotech has gone back over the rumors, the speculation, the sheer guesswork provided by a legion of analysts, to see which biotechs are now the most cited buyout targets in the industry. 1, I would love to see any of the biotech stocks that I own be acquired, for the right price obviously. Antares Pharma (ATRS). Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. Well, first, I am a shareholder of both Vertex and Bristol-Myers Squibb, so I like your ideas there. Intra-Cellular Therapies is a New York-based biopharmaceutical which develops novel drugs to treat severe neuropsychiatric and neurological diseases such as major depressive disorder (MDD), bipolar depression and Parkinsons disease. If you have an ad-blocker enabled you may be blocked from proceeding. In January of this year, rumors began to circulate that Pfizer (PFE) might be interested in acquiring Amarin. One of those stocks was. *Average returns of all recommendations since inception. Therefore, leading companies such as CRISPR Therapeutics, Intellia Therapeutics, or Editas Medicine might catch the eye of large pharmaceutical companies trying to step into this field and complement their pipeline with CRISPR/Cas9 technology. Bayer announced the acquisition of the global strategic imaging AI platform and solutions provider Blackford Analysis Ltd. Aesther Healthcare Acquisition Corp and Ocean Biomedical, Inc. announced that AEHA has filed with the U.S. Securities and Exchange Commission a definitive proxy statement in connection with its proposed business combination with Ocean and with respect to the special meeting of Aesthers stockholders scheduled to be held on February 3, 2023. Keep track of M&A as it happens with this database. Here's the Stock to Buy Now, Join Nearly 1 Million Premium Members And Get More In-Depth Stock Guidance and Research, Motley Fool Issues Rare All In Buy Alert, Copyright, Trademark and Patent Information. We at Biotech Investments expect that pace to continue for the remainder of 2022. Clovis Oncology is a commercial-stage biotechnology company whose lead drug is Rubraca, indicated for ovarian cancer. Dealmaking is essential to the business of drug development. When the symbol you want to add appears, add it to Watchlist by selecting it and pressing Enter/Return. Are you interested in learning more about small- and mid-cap biotech stocks with exceptional growth potential and some of the hottest takeover targets of the industry? *Premiums are calculated from the closing price of the acquired company's shares on the previous trading day. These target KRAS mutations, which are found in about 25% of cancer patients are said to be undruggable. Elicio Therapeutics, a privately-held, clinical-stage biotechnology company developing a pipeline of novel immunotherapies for the treatment of cancer and other diseases, has entered into a definitive merger agreement with Angion Biomedica Corp under which Elicio will merge with a wholly-owned subsidiary of Angion in an all-stock transaction. Sold Sepracor to Dainippon Sumitomo: Mr. Adams served as President and Chief Executive Officer of Sepracor Inc. Dainippon Sumitomo bought out Sepracor for $2.6B, or a 48% premium over the current share price. Neovasc Inc. ("Neovasc" or the "Company") (NASDAQ,TSX: NVCN)announced today that the Company has entered into a binding agreement (the Arrangement Agreement) with Shockwave Medical, Inc. (Shockwave), whereby Shockwave has agreed to acquire all of the issued and outstanding common shares (the Common Shares) of the Company (the Transaction). Additionally, it has a robust gene therapy pipeline, targeting DMD, limb-girdle muscular dystrophies and several other indications. The most recent update provided by the company suggests it may take several quarters for the issue to be resolved. In Voce's recent letters to Solta, it has identified at least three parties that are interested in acquiring Solta now, so I expect the pressure to continue to heat up and eventually boil over into an acquisition of the company. This year has seen a modest rebound after a slow start, and analysts believe a further resurgence is likely. Any you had ideas about? Source: Mongkolchon Akesin / Shutterstock.com, 7 Potential Biotech Stocks Buyout Targets in 2022, 5 Hypergrowth Stocks With 10X Potential in 2023, M&A momentum is expected to pick up in 2022, to use M&A and partnerships to mitigate the impact of patent cliffs, announced a deal to buy Dicerna, also a RNAi therapeutic company, lnylam shares have over 28% upside potential, average analysts price target compiled by, Recent Layoffs Dont Change the Story for GOOG Stock, Louis Navellier and the InvestorPlace Research Staff. Bristol-Myers Squibb (BMY) acquiring Celgene for $74 billion in January remains the most expensive acquisition of this year. Other approved drugs in the companys portfolio continue to do well. Therefore, I am picking 5 best Mid-cap biotech acquisition targets in this post with deal value less than $10B each. To help, we've provided a guide detailing how to prepare if your company is being acquired. At the time, I was . I also agree with you that Vertex, if there's going to be one of those massive big pharma mergers like we've seen over the last 20 years, some of those massive deals, I think Vertex would be an excellent candidate to be acquired by a bigger company. Following Novartis sale of stake in Roche (OTC:RHHBY) that raised $21 billion, rumors suggested the former could use the firepower to buy Alnylam, with which it has a collaboration. Markets. 8. The reason is that their deal is for an over the counter product that Pfizer has in its inventory. The companys drug Ocaliva has been approved for primary biliary cholangitis. The Motley Fool recommends Biogen and Gilead Sciences. Want to Get Richer? The speculation gained further ground when Denmark-based Novo Nordisk (NYSE:NVO) announced a deal to buy Dicerna, also a RNAi therapeutic company. David Callan was actively involved SRI Surgical (Formerly Nasdaq listed STRC) unsolicited offer bid and eventual sale of the company. AMAG Pharmaceuticals (Market Cap $0.7bn) US specialty firm AMAG Pharmaceuticals Inc. is viewed as an acquisition target for companies established in women's health - specifically Novartis AG - due to the potential of bremelanotide in hypoactive sexual desire disorder (HSDD). Learn More. Orelli: I think a pharma that wanted a lot of cash flow, but also wanted to boost up their pipeline, Vertex probably has more external deals than it has internal candidates. Always do your own due diligence before buying and selling any stock, and/or consult with a licensed financial adviser. I'm thinking Intellia (NTLA -1.57%) potentially being acquired by Regeneron (REGN 0.83%), and CRISPR Therapeutics (CRSP 3.66%) potentially being acquired by Vertex Pharmaceuticals (VRTX 3.67%). But I think there's also a good fit on Seagen's pipeline too. Seagen has quite a few oncology drugs that would work well with the Bristol-Myers drugs. After a rather bumpy start with disappointing sales numbers in 2019 and 2020, CAPLYTA net product revenues for the second quarter 2022 showed a 190% increase as compared to the same period in 2021 and a 58% increase over the first quarter 2022. All rights reserved. Please disable your ad-blocker and refresh. The top ten deals in the industry totaled $97 billion in 2020, led by the $39-billion buyout of Alexion Pharmaceuticals ( ALXN) - Get Free Report late in the year by AstraZeneca ( AZN) - Get Free. Speights: Yeah. FTX Fooled the World. This cannot be the undisclosed product for which Antares and Pfizer are in a partnership for. Later, Bristol-Myers Squibb for $2.4B. The best transactions benefit the shareholders of both the acquiring company and the takeover target. Click on an acquiring company to pull up more information, and scroll to the bottom of the page to read how this information was collected and organized. You can see the complete list of todays Zacks #1 Rank (Strong Buy) stocks here. Like the Medicines Co., Amarin also has a heart drug by the name Vascepa in its kitty. There weren't that many biotech acquisitions in 2021, at least, not compared to other previous years. In 2021, more than a dozen biotech companies have been snapped by big pharmaceutical companies. Sold Tercica to Ipsen: Mr. King served as President and General Manager of Tercica. But that deadline has long passed. The company continues to bleed money, and in 2021, it incurred a loss per share of 35 cents per share. There's a company called Adicet Bio (ACET 0.46%), ticker there is ACET, I believe. Even with a market cap of over $2B, we feel Acadia could fetch as much as $6B if the FDA approves pimavanserin, which could happen in the next 6 to 8 months. Editor's note: If tables or values do not display, please try clearing your browser's cache and reloading the page. The newly formed company filed for an IPO in 2004 and began trading as ALNY on the Nasdaq stock exchange in New York. GLOBAL MARKETS-Stocks buoyed by cheery data after BOJ damp squib, Nouriel Roubini: There's a massive disconnect between markets and the Fed, U.S. natgas price slump pushes 'widow maker' toward unusual contango, Germany must speed hydrogen plans this year - gas pipeline group OGE, Ian Bremmer: We're in a hot war with Russia. Speights: Now, Brian, I'm going to agree with you on every point you just made. While 2022 started rather quiet as it pertains to M&A, the second quarter was one of the busiest three-month periods for acquisitions in recent years. Sold GenPharm International, Inc. to Medarex, which was then acquired by Bristol-Myers Squibb (BMY): Mr. Rosen served as Director of Corporate Development at GenPharm International. Are you interested in learning more about small- and mid-cap biotech stocks with exceptional growth potential and some of the hottest takeover targets of the industry? Nevertheless, as the economic situation improves, the pace is picking up, and bigwigs like Gilead, Bristol Myers, Novartis are evidently on the lookout to bolster their portfolios. Cambridge, Massachusetts-based Crisprs lead asset CTX001 is in development for two indications beta thalassemia and sickle cell disease in collaboration with Vertex Pharma. Keith Speights owns Bristol Myers Squibb and Vertex Pharmaceuticals. I don't know. The database, which shows drugmaker acquisitions that happened since 2018 and were valued at $50 million or more in upfront consideration, will be regularly updated. It is running mid-stage clinical trials of the drug, in combination with bezafibrate, in PBC, late-stage studies in non-alcoholic steatohepatitis (NASH) and a mid-stage study in biliary atresia. In addition, the American company has several commercial and research successes, including recent positive Phase 3 clinical trial data for its ATTR amyloidosis drug ONPATTRO (Patisiran). Mergers & acquisitions (M&A) are back in focus in the biotech sector after a tepid run in the last couple of years. Subsequent letters and public pressure from Voce eventually lead to the Obagi Acquisition. Outsmart the market with Smart Portfolio analytical tools powered by TipRanks. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. See the complete list of todays Zacks # 1 Rank ( Strong Buy stocks..., I am a shareholder of both Vertex and Bristol-Myers Squibb ( BMY ) acquiring Celgene $. Am a shareholder of both the acquiring company and the takeover target can! $ 74 billion in January of this year, rumors began to circulate that Pfizer has in its.. 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